Toward High-Accuracy Open-Source Biomolecular Structure Prediction.

C library for high-throughput sequencing data formats

Code for the DISCO model: General Multimodal Protein Design Enables DNA-Encoding of Chemistry

Burrow-Wheeler Aligner for short-read alignment (see minimap2 for long-read alignment)

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

Protein and nucleic acid validation service

The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.

Reduce - tool for adding and correcting hydrogens in PDB files

A dependency-free cross-platform swiss army knife for PDB files.

The Ensembl Variant Effect Predictor predicts the functional effects of genomic variants

A comprehensive library for computational molecular biology

Official code repository for GATK versions 4 and up

Software for biomolecular electrostatics and solvation calculations

bedtools - the swiss army knife for genome arithmetic

Source code for molecular graphics program UCSF ChimeraX

IQ-TREE software version 2: phylogenetics by maximum likelihood

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

Foundation Models for Genomics & Transcriptomics

Official repository for the Boltz biomolecular interaction models

Tools (written in C using htslib) for manipulating next-generation sequencing data