Issues

• Declare assay-specific applicability of donor and specimen independence claims

  pirl-unc/hitlist#706 · Filter by author iskandr opened on Oct 16, 2026

• Review Atlas community SDRF, acquisition aliases and QC inclusion before resolving specimens

  pirl-unc/hitlist#705 · Filter by author iskandr opened on Oct 16, 2026

• Align supported Python baseline and CI with Python 3.10–3.14

  pirl-unc/hitlist#684 · Filter by author iskandr opened on Oct 15, 2026

• Qualify reviewed experimental and specimen lineage for frozen training holdouts

  pirl-unc/hitlist#680 · Filter by author iskandr opened on Oct 15, 2026
  1

• Track a frozen, audited training-data release for MHCflurry 3.x and Presto

  pirl-unc/hitlist#678 · Filter by author iskandr opened on Oct 15, 2026
  9

• Qualify and curate Miyamae 2026 ten-allele canine DLA-88 ligand atlas

  pirl-unc/hitlist#677 · Filter by author iskandr opened on Oct 13, 2026

• Acquire Lang 2026 splenic DLA-DR MS peptide data before curation (PMID 42752862)

  pirl-unc/hitlist#676 · Filter by author iskandr opened on Oct 13, 2026
  1

• Track normal heart, brain and lung DLA ligand coverage from resolved canine donors

  pirl-unc/hitlist#674 · Filter by author iskandr opened on Oct 12, 2026
  1

• Integrate released orfdata protein summaries and subsequent canine peptide evidence

  pirl-unc/hitlist#668 · Filter by author iskandr opened on Oct 12, 2026
  1

• Curate canine normal-tissue bulk MS from Pfizer and Labrador PeptideAtlas with explicit assay and donor scope

  pirl-unc/hitlist#666 · Filter by author iskandr opened on Oct 9, 2026

• Cancel superseded PR validation runs without interrupting main releases

  pirl-unc/hitlist#656 · Filter by author iskandr opened on Oct 7, 2026

• Correct Bekker-Jensen search and protocol provenance for detectability labels

  pirl-unc/hitlist#654 · Filter by author iskandr opened on Oct 7, 2026
  2

• Investigate fragmented observation-export blocks and increased warning count

  pirl-unc/hitlist#642 · Filter by author iskandr opened on Oct 6, 2026

• Reconcile Ramarathinam 2021 publication and deposited peptide coverage (PMID 34357683)

  pirl-unc/hitlist#632 · Filter by author iskandr opened on Oct 2, 2026

• Non-roster single-molecule mouse designations (H2-Kbm1, H2-K*wm7) stay two_digit: 7 rows, and the bm series would be refused

  pirl-unc/hitlist#606 · Filter by author iskandr opened on Sep 28, 2026

• Haplotype parse results fall through to "unresolved": 15,596 rows carry a class-scoped statement over a known allele list

  pirl-unc/hitlist#604 · Filter by author iskandr opened on Sep 28, 2026
  1

• Two whole-frame copies of the 4.4M-row index drop 0.95% of its rows (6.7 GB)

  pirl-unc/hitlist#603 · Filter by author iskandr opened on Sep 28, 2026
  1

• expand_allele_set refuses gene-level and serological restrictions before the candidate lookup: 270,743 rows unattributed with a pool in hand

  pirl-unc/hitlist#599 · Filter by author iskandr opened on Sep 28, 2026

• engineering_drift_audit: 71 arms silent on an engineering column a sibling asserts

  pirl-unc/hitlist#593 · Filter by author iskandr opened on Sep 27, 2026
  1

• Soluble-HLA arms do not record soluble_mhc (26768311, 23543059)

  pirl-unc/hitlist#588 · Filter by author iskandr opened on Sep 27, 2026
  1

• Ten object-dtype columns ride through the 4.4M-row join for five per-arm constants

  pirl-unc/hitlist#572 · Filter by author iskandr opened on Sep 26, 2026
  1

• No bulk RNA-seq for HAP1 / C1R / 721.221 — the lines carrying every APM perturbation study

  pirl-unc/hitlist#358 · Filter by author iskandr opened on Aug 26, 2026
  3

• Curate source_tissue / cell type for PMIDs with blank provenance (PRAME '(unspecified)' rows)

  pirl-unc/hitlist#314 · Filter by author iskandr opened on Jun 9, 2026
  1

• Profile + optimize observations.parquet and peptide_mappings.parquet build steps

  pirl-unc/hitlist#176 · Filter by author iskandr opened on Apr 28, 2026
  4

• Per-arm modifications column for Bekker-Jensen bulk proteomics (follow-up to #94)

  pirl-unc/hitlist#96 · Filter by author iskandr opened on Apr 20, 2026