This repository describes a workflow for automated PD-L1 scoring of Tumor Proportion Score (TPS), Combined Positive Score (CPS) and Immune Cell Score (ICS) with QuPath and MATLAB.
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Updated
Apr 27, 2022 - Groovy
This repository describes a workflow for automated PD-L1 scoring of Tumor Proportion Score (TPS), Combined Positive Score (CPS) and Immune Cell Score (ICS) with QuPath and MATLAB.
Reproducible Pan-Cancer transcriptomic analysis pipeline evaluating immune cell infiltration (CIBERSORT) and immune checkpoint expression (PD-L1/CTLA-4) across TCGA cohorts.
OmniScreen-AI: Multi-modal AI drug screening for PD-L1 — small molecules, peptides & nucleic acids. RDKit · AutoDock Vina · ESM-2 · AlphaFold3 · OpenMM · MM-PBSA. Notebook-driven Colab→GPU pipeline.
AnimaFlow-AI: End-to-end AI drug-discovery methodology hub — single-cell & spatial omics → virtual-cell target ID → multimodal screening (small molecule / peptide / nucleic acid). Case studies: COVID-19, kidney, PD-L1.
myeloid cells isolated from liver tissue and FACS sorted as CD11c+MHC2+CD45+CD3-B220- for bulk seq and pathway enrichment analysis. cells isolated from WT or Pdl1CyMt mice fed High fat high cholesterol diet for 22 weeks. 2exps icluded
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