A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.
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Updated
Oct 3, 2026
A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.
Embodied Drosophila: 138,639-neuron whole-brain connectome simulation (FlyWire v783) in a biomechanical body (NeuroMechFly v2 / MuJoCo). Vision, olfaction, gustation, flight, and emergent behaviors — all from the real connectome.
把果蝇全脑连接组跑在一台 16GB 笔记本上:接身体、做成浏览器游戏(Running the whole Drosophila brain connectome on a 16 GB laptop, wiring it to a body, shipping it as a browser game )
High-performance C++ reimplementation of flygym/NeuroMechFly on MuJoCo, with spiking connectome integration
What a fly connectome adds to controlling a body: a reproducible comparison of the Drosophila connectome, a two-line rule and shuffled networks on an identical NeuroMechFly body
Python bridge for flygame: high-performance flygym/NeuroMechFly on MuJoCo
60 FPS engine-free 3D pond in ~2.3k lines of Python: 9 fly agents, one driven by LIF spiking circuits (GF/CX/REST) — plus the real NeuroMechFly model (126 DoF, 721 ommatidia/eye) assembled and rendered on MuJoCo.
A physically simulated fruit fly (NeuroMechFly + MuJoCo) with a live whole-brain created to suffer for eternity.
In-browser 3D bio-robotic simulation where Carla, a fruit fly (Drosophila melanogaster), drives a classic Mini Cooper using the NeuroMechFly v2 biomechanical model, the MaleCNS neural connectome, and MuJoCo WebAssembly physics.
Two whole-CNS Drosophila connectomes in one local explorer, and the 166,700-neuron MaleCNS brain wired up as a spiking network driving a NeuroMechFly body in MuJoCo
The FlyWire connectome of a fruit fly answering LeetCode problems.
Closed-loop simulated Drosophila: a 139k-neuron FlyWire v783 connectome spiking brain driving a FlyGym/MuJoCo body, doing odour-driven walking on a GTX 1080 Ti.
Teaching a life-sized fruit fly to hit a baseball 🪰⚾ — NeuroMechFly body, MaleCNS connectome circuit, MuJoCo physics.
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