Predict the direction of a CpG's effect on gene expression. Four evidence layers — measured eQTMs, summary-data Mendelian randomisation, per-tissue gradient-boosted models, and a distance prior — over 3.1M CpG-gene pairs. Calibrated, tiered, and abstains where the evidence is thin.
bioinformatics gene-expression epigenetics r-package dna-methylation mendelian-randomization smr eqtm illumina-epicv2 epigenomewideassociation
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Updated
Oct 13, 2026 - R