R code for the simulation study in the paper by Kristen M Cunanan et al. (2019). Variance prior specification for a basket trial design using Bayesian hierarchical modeling.
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Feb 3, 2023 - R
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basket-trial
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896 tests / 42 scripts validating Zetyra calculators (GSD, CUPED, Bayesian, SSR incl. Single-Arm, RAR, Master Protocol). Replicates 8 published trials (Salk, DAPA-HF, PACIFIC, MONALEESA-7, I-SPY 2, STAMPEDE, REMAP-CAP, NCT03377023) + Leyrat 2024.
python r validation monte-carlo fda biostatistics clinical-trials bayesian sample-size oncology adaptive-design prior-elicitation cuped group-sequential-designs basket-trial master-protocol statistical-validation bayesian-toolkit platform-trial nct03377023
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May 15, 2026 - Python
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