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TPL_bioheat_model

1-D Three-Phase Lag model

Skin Layers:

epidermis, dermis, subcutaneous

Heat sources:

  • blood perfusion (dermis, subcutaneous)
  • metabolic heat (all)
  • water diffusion (all)
  • vaporization (epidermis)
  • hyperthermia device (modeled as Gaussian volume, targeted at tumor location)

Scripts

  • changing_tau_final.m: Performs the analysis under 'Varying Tau Parameters'
  • a0_test_final.m & power_test_final.m: Performs the analysis under 'Varying Targeted Heat Source Parameters'
  • skin_layer_comparison.m: Performs the analysis under 'Impact of Skin Layers and Heat Sources'
  • main_final.m: Runs the model with optimized parameters

Reference Papers:

[1] Kumar, M., Upadhyay, S., Singh, S., & Rai, K. N. (2023). Mathematical modelling and simulation of three phase lag bio-heat transfer model during cancer treatment. International Journal of Thermal Sciences, 184, 108002.

[2] Kumari, T., Kumar, D., Rai, K. N., & Singh, S. K. (2023). Numerical solution of DPL heat transfer model in multi-layer biological skin tissue of the living body during hyperthermia treatment. Mechanics Based Design of Structures and Machines, 51(1), 159-178.

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