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Model-selection blog series: in silico study of splicing scores under a fixed minigene budget; manuscript and reproduction migration in progress

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Splicing scores for a fixed minigene budget

Standalone study repository, migrated from the model-selection article series.

Status

The original measurements and code are imported. A LaTeX manuscript reporting these existing results is in paper/main.tex, with the compiled PDF at paper/build/main.pdf. Rebuild it with make paper-imported (system Python and local TeX Live only; it formats archived metrics and compiles, and runs no experiment, data download or environment creation). Provenance for the manuscript is in evidence/paper-migration/: claims ledger, content-coverage map, build receipt, independent AI review and status.

Independent reproduction is pending: protocol.md (draft v2, unapproved) incorporates corrections from an automated AI methods review of draft v1 and has not been executed. The generic harness configuration is unconfigured and must not be used to claim verified results. Follow the companion README for the original runnable workflow. No new experiment, human approval, human review or independent reproduction is claimed by this migration.

The repository will hold the detailed methods and paper; the blog will provide a shorter accessible explanation. Original third-party licences and notices remain applicable; no blanket relicensing is applied.

Validation and review

Run make test for the maintained companion's offline tests. Data-dependent tests skip until the companion workflow has produced its inputs; a green offline check is not a scientific reproduction. Push and pull-request CI also validates archived manuscript tables. The historical archives are unchanged. See the review record for findings, fixes and remaining reproduction limits.

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Model-selection blog series: in silico study of splicing scores under a fixed minigene budget; manuscript and reproduction migration in progress

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