Hi,
I was wondering whether you have compared using all genes vs. only highly variable genes (HVGs) as input for the multi-dimensional scaling step? The reason I ask is that HVGs are often used as input for other dimensionality reduction methods, such as PCA.
Best wishes,
Lucy
Hi,
I was wondering whether you have compared using all genes vs. only highly variable genes (HVGs) as input for the multi-dimensional scaling step? The reason I ask is that HVGs are often used as input for other dimensionality reduction methods, such as PCA.
Best wishes,
Lucy