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1. 修复多处变量命名冲突问题，将所有名为var的局部变量重命名为var_ 2. 更新注释中匹配的变量名描述，保持代码可读性一致 3. 新增seqcode_demo示例项目与完整的SeqUtils高级功能测试用例 4. 更新README文档，补充SeqUtils功能说明与测试用例数量
新增了三个R/Bioconductor工具的MoonBit移植实现： 1. pqs_finder：G-四链体(PQS)检测工具，支持自定义评分与链搜索 2. dnacopy：基于CBS循环二分分割的拷贝数分析工具 3. regione_r：基因组区域置换检验工具，支持随机化与mask 同时添加了对应的完整测试用例与示例程序，更新README文档说明新增模块与示例。
新增了从Biopython移植的完整解链温度计算功能，包括Wallace法则、GC经验公式、近邻热力学算法，支持多种盐/镁离子/化学添加剂校正、错配与悬挂末端处理。同时添加了对应的示例程序与8000+行的单元测试，更新README文档与项目示例列表。
添加了完整的minet模块实现，包括离散化、熵估计、互信息计算、ARACNE/CLR/MRNET三种网络推断方法，以及验证评分功能；新增示例demo和测试用例，更新README文档说明。
移植Biopython Bio.Align的MSA统计能力： 1. 新增alignment_letter_counts实现列字母计数与频率计算 2. 新增alignment_substitution_matrix实现对称替换计数矩阵 3. 配套添加完整的单元测试与示例demo 4. 更新README文档与项目统计信息
- 实现 pi0est 支持三次光滑样条与闭形式自助法两种pi0估计 - 新增 lfdr 局部FDR计算，支持probit/logit变换与高斯KDE - 实现 pooled/test-specific 经验p值计算 - 完整 qvalue 分析流程，支持pFDR校正与fdr.level显著性筛选 - 添加 qvalue_demo 示例与400+单元测试用例 - 更新文档与测试计数统计
新增了从Biopython C聚类库移植的数值聚类功能，包括8种距离计算、层次聚类、k-means/k-medoids、SOM、PCA以及Eisen Cluster/TreeView格式读写支持，同时添加了完整的示例程序和测试用例，更新了文档说明与测试计数。
1. 重构pqsfinder核心搜索逻辑，新增pqs_search函数返回density和max_scores逐位置统计向量 2. 实现overlapping模式，支持导出所有符合条件的PQS构象并去重保留最高分 3. 新增Pqs::sequence方法支持提取PQS命中的序列 4. 更新示例程序，新增deep搜索、重叠构象展示和序列提取的演示 5. 补充大量单元测试覆盖新功能 6. 更新README文档和项目说明，同步功能变更 7. 调整测试用例计数，更新统计信息
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