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nshen7 merged 1 commit into from
Jul 12, 2025
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Update README.md #9

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5 changes: 3 additions & 2 deletions README.md
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<p style="text-align: center;">
<img src="man/figures/logo.png" alt="Example Image" width="70">
<p align="center">
<img src="man/figures/logo.png" alt="Example Image" width="160">
</p>


# vmrseq: Detecting variably methylated regions (VMRs) from single-cell bisulfite sequencing

The R package `vmrseq` is a novel computational tool developed for pinpointing variably methylated regions (VMRs) in scBS-seq data without prior knowledge on size or location. High-throughput single-cell measurements of DNA methylation allows studying inter-cellular epigenetic heterogeneity, but this task faces the challenges of sparsity and noise. vmrseq overcomes these challenges and identifies variably methylated regions accurately and robustly.
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