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Precise identification of cancer cells from allelic imbalances in single cell transcriptomes

DOI

This repository contains all R scripts to perform the analysis in our manuscript, "Precise identification of cancer cells from allelic imbalances in single cell transcriptomes."

alleleIntegrator is an R package that integrates whole genome sequencing of tumour DNA and single cell RNA sequencing of a tumour to identify which single cells are cancer derived. For a detailed description of the method, as well as a vignette, please visit https://github.com/constantAmateur/alleleIntegrator

Citation

If you use this package in your work, please cite: Trinh, M.K, et al., Precise identification of cancer cells from allelic imbalances in single cell transcriptomes, BiorXiv, 2021

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