Local BLAST Studio v0.4.0

Local BLAST Studio v0.4.0

Highlights

• Added BLASTN/BLASTP Align 3+ sequences mode using local Clustal Omega (clustalo).
• Reworked the app shell with a top workspace bar and persistent, resizable Results panel.
• Added full result detail viewing from the Results workspace.
• Added result re-use for new searches using local sidecar metadata saved with new runs.
• Added multi-result selection, export, delete, delete-all confirmation, and right-click result actions.
• Improved alignment/raw viewing with larger text, raw default for alignments, citation filtering, and top-anchored alignment output.

External tools

Local BLAST Studio does not bundle BLAST+, IgBLAST, or Clustal Omega. Install the tools separately and configure the bin directory in Tools. See the README for Homebrew and Conda/Bioconda install commands.

macOS note

This DMG is ad-hoc signed but not notarized. If macOS quarantines the app after dragging it into Applications, run:

xattr -dr com.apple.quarantine /Applications/LocalBlastStudio.app

Local BLAST Studio v0.3.0

What's new

• Adds the Results workspace for multiple BLAST jobs and saved result files.
• Auto-loads .txt, .tsv, and .out reports into a GUI with Descriptions, Alignments, Table, and Raw panes.
• Tracks running, finished, failed, and imported jobs with output sizes, hit counts, and runtime metadata.
• Avoids overwriting previous runs by giving repeated outputs unique timestamped paths.
• Raises the default BLAST thread count to 4 for faster local searches.
• Expands database recommendation docs for starter databases, RNA-Seq annotation, taxonomy, storage, and performance planning.

Validation

• swift build
• swift run LocalBlastSmokeTests
• hdiutil verify dist/BLAST-Studio-0.3.0-universal.dmg

Asset checksum

BLAST-Studio-0.3.0-universal.dmg

SHA-256: 2acdbbdfbd62cb97ca6fa098658d7151de4841397048e88c88c90fad3b51c5cb

BLAST Studio v0.2.0

BLAST Studio v0.2.0

This release includes:

• RNA-Seq annotation workspace for trimmed or merged FASTQ/FASTQ.GZ inputs.
• Download progress panel with speed, time-left ETA, and estimated finish time.
• Recommended starter databases: core_nt for BLASTN and nr_cluster_seq for BLASTP.
• Direct ClusteredNR download support for nr_cluster_seq.
• Pairwise sequence comparison workflow using BLAST+ subject mode.
• Sequence text boxes that wrap pasted sequences without continuation hyphens.
• macOS universal DMG for Intel and Apple Silicon Macs.

The app still runs BLAST locally and does not bundle NCBI BLAST+ binaries or databases.

BLAST Studio v0.1.0

Update README.md