MIMESIS is a computational workflow to quantify and classify tumor signals in tissue and cfDNA samples.
Romagnoli, Dario et al. “MIMESIS: minimal DNA-methylation signatures to quantify and classify tumor signals in tissue and cell-free DNA samples.” Briefings in bioinformatics vol. 24,2 (2023): bbad015.
You can install the development version of MIMESIS from GitHub with:
# install.packages("devtools")
devtools::install_github("cgplab/MIMESIS")
devtools::install_github("cgplab/PAMES")library(MIMESIS)
library(PAMES)
## basic example code
samples_subtype <- classify_samples(bc_data)
samples_purity <- get_purity(bc_data, bc_sites)