Release 2026.2.4#695
Merged
Merged
Conversation
Both statement layers serialize with type "Statement"; document distinguishing them via proposition.type and correct the pathogenicity example to use the GA4GH schema values. Add a warning that the pathogenicity classification reflects MaveDB functional evidence only, not a complete clinical determination.
Add a heuristic table mapping a variant's state (mapped, scored, calibrated) to the highest VA-Spec layer it qualifies for, consolidating the per-variant availability rules previously only described in prose. Also document that a score falling outside every calibration range is annotated at the layer above as Indeterminate/Uncertain Significance with a Neutral direction, rather than demoted to a lower layer.
Align classification, direction, strength, and evidenceOutcome code values in the examples, prose, and tables with the lowercase form MaveDB actually emits (e.g. `pathogenic`, `abnormal`, `supports`), and note the convention so consumers do not match on the wrong casing. ACMG criterion codes such as `PS3` and `BS3_supporting` keep their conventional casing.
…dentification VA-Spec Documentation Updates
Bumps direct deps axios -> ^1.18.1, dompurify -> ^3.4.11, lodash -> ^4.18.1 and applies npm audit fix for transitive packages to clear Dependabot alerts. Pins pdbe-molstar back to 3.4.0 to keep molstar on 4.8.0 (5.x requires node >=22; CI runs node 20); the bump was incidental churn, not a security fix. Remaining alerts require major bumps (vite/vitest, openapi-typescript, uuid) tracked in #696; elliptic has no patch available.
- Add AVE Alliance entry to the PARTNERS array on the About page - Add AVE_ALLIANCE_URL to centralized links module - Commit AVE Alliance logo as a static asset Closes #692
…iance-partner feat(about): add AVE Alliance to partners & collaborators
This file contains hidden or bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment
Add this suggestion to a batch that can be applied as a single commit.This suggestion is invalid because no changes were made to the code.Suggestions cannot be applied while the pull request is closed.Suggestions cannot be applied while viewing a subset of changes.Only one suggestion per line can be applied in a batch.Add this suggestion to a batch that can be applied as a single commit.Applying suggestions on deleted lines is not supported.You must change the existing code in this line in order to create a valid suggestion.Outdated suggestions cannot be applied.This suggestion has been applied or marked resolved.Suggestions cannot be applied from pending reviews.Suggestions cannot be applied on multi-line comments.Suggestions cannot be applied while the pull request is queued to merge.Suggestion cannot be applied right now. Please check back later.
Features
Bug Fixes
N/A
Maintenance