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@SBBlaboratory

Systems Biology and Bioinformatics Laboratory (SBBL)

Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea

Systems Biology & Bioinformatics Laboratory (SBBL)

Multi-omics • Artificial Intelligence • Computational Biology

Website GitHub Org


Analyzing Multi-Omics and Developing computational methods to understand genome, epigenome, and cellular heterogeneity.


🔬 Research Areas

🧬 Single-cell & Spatial Multi-omics

  • Single-cell RNA-seq
  • Single-cell Epigenomics
  • Strand-seq
  • Spatial Transcriptomics
  • Multi-omics Integration

🤖 Artificial Intelligence for Biology

  • Machine Learning
  • Deep Learning
  • Foundation Models for Biology
  • Large Language Models (LLMs) for Biology

🧪 Computational Genomics

  • Somatic Mosaicism
  • Structural Variant
  • Genome Instability
  • Aging
  • Cancer Evolution
  • Gene Regulatory Networks

🚀 Featured Projects

Project Description
scNOVA-related tools Single-cell nucleosome occupancy analysis with Strand-seq
CellTyper LLM-based cell-type annotation agent
Multi-omics pipelines End-to-end analysis workflows

💻 Technologies

Languages

Python R

AI

PyTorch Transformers LangGraph OpenAI API CNN LLM LangChain Deep Learning

Bioinformatics

Seurat Scanpy Bioconductor AnnData Single-cell

Infrastructure

Docker Linux CUDA GitHub Actions


📚 Research Interests

  • AI-guided Bioinformatics
  • Multi-omics Integration
  • Single-cell Biology
  • Computational Genomics
  • Cancer Evolution
  • Aging

🌐 Website

https://www.sbblaboratory.com


🤝 Open Source

We believe reproducible science starts with open software.

This organization hosts software, datasets, and computational tools developed in the Systems Biology & Bioinformatics Laboratory.

Contributions, issues, and discussions are always welcome.


MultiOmics to link genome & epigenome

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  1. scNOVA scNOVA Public

    Forked from jeongdo801/scNOVA

    scNOVA : Single-Cell Nucleosome Occupancy and genetic Variation Analysis

    R

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