PhD candidate at UCSF & the Arc Institute — working across functional genomics, virology, and AI-enabled research systems.

Website · Google Scholar · ORCID · LinkedIn

I'm a PhD candidate in the Biological & Medical Informatics program at UCSF, jointly mentored by Luke Gilbert and Brian Hie at the Arc Institute. My research sits at the intersection of functional genomics, virology, and computational biology — combining CRISPR-based screening, assay development, and high-dimensional data analysis to study gene regulation, host–virus interactions, and disease mechanisms.

In parallel, I build AI-enabled research systems — LLM councils, research agents, APIs, and multi-agent workflows for literature synthesis, hypothesis generation, and experimental planning.

Before UCSF, I spent nearly three years at the Broad Institute on the Cancer Dependency Map, applying statistical modeling and machine learning to genome-scale perturbation data to discover and validate cancer targets.

• CRISPR functional genomics — genome-scale knockout, interference, and Perturb-seq screens
• Virology & host–virus biology — assay platforms and perturbation systems for infection biology
• AI-enabled research systems — LLM councils, research agents, and multi-agent workflows
• Computational ↔ experimental loops — closing the gap between in-silico predictions and bench validation

• Building agentic systems for scientific discovery and analysis
• Running screens to discover protein function
• Reading to build new biological systems

• mTORC1 activity suppresses ferroptosis through a SCARB1-dependent HDL–tocopherol uptake pathway — Molecular Cell (2026)
• SKI complex loss renders 9p21.3-deleted or MSI-H cancers dependent on PELO — Nature (2025)
• Integrated epigenetic and genetic programming of primary human T cells — Nature Biotechnology (2025)
• A systematic search for RNA structural switches across the human transcriptome — Nature Methods (2024)
• Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer — Cell (2021)

Full list on Google Scholar or my CV.

Python · R · PyTorch · scanpy · Snakemake · Nextflow · Docker

The fastest route is email — details on my website. Always happy to talk about CRISPR screens, virology, AI tooling for science, or grad life at UCSF and the Arc Institute.