From 2306d1010bb90781d444eb37103176cb968e0d0f Mon Sep 17 00:00:00 2001
From: Ning Shen <38674209+nshen7@users.noreply.github.com>
Date: Sat, 12 Jul 2025 11:44:22 -0700
Subject: [PATCH] Update README.md
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# vmrseq: Detecting variably methylated regions (VMRs) from single-cell bisulfite sequencing
The R package `vmrseq` is a novel computational tool developed for pinpointing variably methylated regions (VMRs) in scBS-seq data without prior knowledge on size or location. High-throughput single-cell measurements of DNA methylation allows studying inter-cellular epigenetic heterogeneity, but this task faces the challenges of sparsity and noise. vmrseq overcomes these challenges and identifies variably methylated regions accurately and robustly.