From 6cbb970154c3687527a655337640f3fc3e033fa5 Mon Sep 17 00:00:00 2001
From: mite-bot <zdoucmm@gmail.com>
Date: Tue, 14 Apr 2026 15:09:58 +0200
Subject: [PATCH 1/2] Add submission UUID file

---
 .../ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json | 44 +++++++++++++++++++
 1 file changed, 44 insertions(+)
 create mode 100644 mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json

diff --git a/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json b/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json
new file mode 100644
index 00000000..41756677
--- /dev/null
+++ b/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json
@@ -0,0 +1,44 @@
+{
+    "accession": "MITE9999999",
+    "status": "pending",
+    "changelog": [
+        {
+            "version": "1",
+            "date": "2026-04-14",
+            "contributors": [
+                "0000-0001-5730-3326"
+            ],
+            "reviewers": [
+                "BBBBBBBBBBBBBBBBBBBBBBBB"
+            ],
+            "comment": "New entry."
+        }
+    ],
+    "enzyme": {
+        "name": "NysDI",
+        "databaseIds": {
+            "uniprot": "Q9L4W6",
+            "genpept": ""
+        },
+        "references": [
+            "doi:"
+        ]
+    },
+    "reactions": [
+        {
+            "evidence": {
+                "evidenceCode": [],
+                "references": [
+                    "doi:"
+                ]
+            },
+            "reactions": [
+                {
+                    "products": [
+                        ""
+                    ]
+                }
+            ]
+        }
+    ]
+}
\ No newline at end of file

From b149cfd7665cd0ee4f7e09580b449a40befae06c Mon Sep 17 00:00:00 2001
From: mite-bot <zdoucmm@gmail.com>
Date: Tue, 14 Apr 2026 15:15:57 +0200
Subject: [PATCH 2/2] Update submission

---
 .../ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json | 39 ++++++++++++-------
 1 file changed, 25 insertions(+), 14 deletions(-)

diff --git a/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json b/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json
index 41756677..2cf0f4c0 100644
--- a/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json
+++ b/mite_data/data/ee4462c4-3802-11f1-8f25-9b0d34c97d5b.json
@@ -16,29 +16,40 @@
     ],
     "enzyme": {
         "name": "NysDI",
+        "description": "glycosyltransferase",
+        "references": [
+            "doi:10.1007/s00253-004-1802-4"
+        ],
         "databaseIds": {
             "uniprot": "Q9L4W6",
-            "genpept": ""
-        },
-        "references": [
-            "doi:"
-        ]
+            "genpept": "AAF71773.1",
+            "mibig": "BGC0000115"
+        }
     },
     "reactions": [
         {
-            "evidence": {
-                "evidenceCode": [],
-                "references": [
-                    "doi:"
-                ]
-            },
+            "tailoring": [
+                "Glycosylation"
+            ],
+            "description": "Presumably responsible for glycosylation of a nystatin aglycone at C19",
+            "reactionSMARTS": "[#6:1]\\[#6@@:2]1-[#6@@:50](\\[#8:51])-[#6@@:48](/[#6:49])-[#6@:46](\\[#6:47])-[#8:45]-[#6:44](=[#8:52])-[#6:43]-[#6@:41](\\[#8:42])-[#6:40]-[#6@:38](\\[#8:39])-[#6:37]-[#6@:35](\\[#8:36])-[#6:34]-[#6:33]-[#6:32]-[#6@:30](/[#8:31])-[#6:29]-[#6:28]2-[#8:53]-[#6@:20](-[#6@@:21](-[#6@:25](-[#6:27]-2)\\[#8:26])/[#6:22](=[#8:24])-[#8:23])\\[#6:19]-[#6@@:17](\\[#8:18])-[#6:16]=[#6:15]-[#6:14]=[#6:13]-[#6:12]=[#6:11]-[#6:10]=[#6:9]-[#6:8]-[#6:7]-[#6:6]=[#6:5]-[#6:4]=[#6:3]-1>>[#6:1]\\[#6@@:2]1-[#6@@:50](\\[#8:51])-[#6@@:48](/[#6:49])-[#6@:46](\\[#6:47])-[#8:45]-[#6:44](=[#8:52])-[#6:43]-[#6@:41](\\[#8:42])-[#6:40]-[#6@:38](\\[#8:39])-[#6:37]-[#6@:35](\\[#8:36])-[#6:34]-[#6:33]-[#6:32]-[#6@:30](/[#8:31])-[#6:29]-[#6:28]2-[#8:53]-[#6@:20](-[#6@@:21](-[#6@:25](-[#6:27]-2)\\[#8:26])/[#6:22](=[#8:24])-[#8:23])\\[#6:19]-[#6@@:17](\\[#8:18]\\[#6@@]2-[#8]-[#6@](\\[#6])-[#6@@](/[#8])-[#6@](\\[#7])-[#6@@]-2\\[#8])-[#6:16]=[#6:15]-[#6:14]=[#6:13]-[#6:12]=[#6:11]-[#6:10]=[#6:9]-[#6:8]-[#6:7]-[#6:6]=[#6:5]-[#6:4]=[#6:3]-1",
             "reactions": [
                 {
+                    "substrate": "C[C@@H]1[C@H](O)[C@@H](C)/C=C/C=C/CC/C=C/C=C/C=C/C=C/[C@H](O)C[C@@H]2OC(C[C@@H](O)CCC[C@@H](O)C[C@@H](O)C[C@@H](O)CC(=O)O[C@H]1C)C[C@H](O)[C@H]2C(=O)O",
                     "products": [
-                        ""
-                    ]
+                        "C[C@@H]1[C@H](O)[C@@H](C)C=CC=CCCC=CC=CC=CC=C[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@H]2OC(C[C@@H](O)CCC[C@@H](O)C[C@@H](O)C[C@@H](O)CC(=O)O[C@H]1C)C[C@H](O)[C@H]2C(=O)O"
+                    ],
+                    "isIntermediate": true
                 }
-            ]
+            ],
+            "evidence": {
+                "evidenceCode": [
+                    "Knock-out studies"
+                ],
+                "references": [
+                    "doi:10.1007/s00253-004-1802-4"
+                ]
+            }
         }
     ]
 }
\ No newline at end of file