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| 1 | +--- |
| 2 | +title: Neurolinguistics |
| 3 | +date: 2025-06-17 |
| 4 | +--- |
| 5 | + |
| 6 | +# Neurolinguistics |
| 7 | + |
| 8 | +## What is Newrolinguistics? |
| 9 | + |
| 10 | +### Human brain - crash course |
| 11 | +- two hemispheres |
| 12 | + - each into four lobes |
| 13 | + - Frontal lobe (Executive functions such as attention, planning, decission making) |
| 14 | + - Temporal lobe (Language, auditory processing) |
| 15 | + - Parietal lobe (Spatial cognition, sensory information) |
| 16 | + - Occipital lobe (Vision) |
| 17 | + |
| 18 | +The role of lobes may be similar across hemispheres, there are also hemispheric differences, called **lateralization.** |
| 19 | +- Split-brain patients providesome evidence for this. |
| 20 | + |
| 21 | +## Aphasia and the origin of neurolinguistics |
| 22 | + |
| 23 | +### How to study language before neuroimaging |
| 24 | +Study impaired language, as different types of **apahsias**. Aphasia arises from brain damage of some sort, common causes include: |
| 25 | +- Stroke |
| 26 | +- Traumatic brain injuries |
| 27 | +- Neurodegenerative diseases |
| 28 | +- Resective surgery (to treat epilepsy) |
| 29 | + |
| 30 | +Rationale is known as the **deficit-lesion method**. |
| 31 | +- Logic: If the individual cannot do X behavior, then the execution of X must depend on the lesioned area. |
| 32 | +- Questions: Moral questions, conclusion |
| 33 | + |
| 34 | +### Broca's aphasia |
| 35 | +Paul Broca and the patient "Tan" (1861) |
| 36 | +- Broca's area |
| 37 | + |
| 38 | +Characteristics of Broca's aphasia: |
| 39 | +- Slow, laborious, non-fluent speech with few if any grammatical morphemes. |
| 40 | +- Comprehension relatively intact, but writing is limited. |
| 41 | + |
| 42 | +### Fluent (Wernicke's) aphasia |
| 43 | +Carl Wernicke's subsequent discovery (1874) |
| 44 | + |
| 45 | +Characteristics of Fluent (Wernicke's) aphasia: |
| 46 | +- Fluent but disordered speech and writing. |
| 47 | +- Frequent substitutions of real words with nonsense words. |
| 48 | +- impaired understanding of speech and writing. |
| 49 | + |
| 50 | +### How much can we learn from aphasias |
| 51 | +Get an idea of where and how language is organized in the brain by comparing behavior and lesson sites. Many disadvantages of relying on apasia studies: |
| 52 | +- Inter-individual variability, no patients are identical, and difficult to replicable. |
| 53 | +- Lot of reorganization can happen during recovery. |
| 54 | +- Moral concerns. |
| 55 | + |
| 56 | +## Modern neuroimaging techniques |
| 57 | + |
| 58 | +### Overview of modern neuroimaging techniques |
| 59 | +To investigate what the brain does, whare it does it, and when it does it. |
| 60 | +- Structural imagining (measuring the structure of the brain) |
| 61 | +- Functional imagining (measuring an aspect of brain function) |
| 62 | + - Non-invasive techniques (PET, fMRI, EEG, MEG etc.) |
| 63 | + - Invasive techniques (electrocorticography, single cell recordings) |
| 64 | + |
| 65 | +### Hemodynamic techniques (PET & fMRI) |
| 66 | +Measure blood, a dependent measure of neural activity |
| 67 | +- PET: Positron Emission Tomography |
| 68 | +- fMRI: Functional Magnetic Resonance Imagining |
| 69 | + |
| 70 | +Increase in neuronal activity -> Increase in metabolic demand for glucose and oxygen -> Increase in cerebral blood flow to the activated region |
| 71 | + |
| 72 | +Measures the work of the brain after it has happened. |
| 73 | +Hemodynamic techniques have excellent spatial resolution but bad temporal resolution. |
| 74 | + |
| 75 | +### Electrophysiological techniques (EEG & MEG) |
| 76 | +Measure actual electrical activity of neurons |
| 77 | +- EEG: Electroencephalography |
| 78 | +- MEG: Magnetoencephalography |
| 79 | + |
| 80 | +Neurons use electricity to communicate with each other -> Neuronal networks fire in synchrony -> the correlates of this combined electrical activity can be measured |
| 81 | + |
| 82 | +Measures the work of the brain as it is happening |
| 83 | +Electrophysiology conditions |
| 84 | + |
| 85 | +## Some classic and modern findings |
| 86 | + |
| 87 | +### Case studies |
| 88 | +- Using modern neurolinguistics |
| 89 | + |
| 90 | +#### Phonemes in the brain |
| 91 | +Phillips et al. (2000): Does auditory cortex have access to phonemic categories? And when is phonemic category information accessed? |
| 92 | + |
| 93 | +Major Obstacle: To prove that any results are due to crossing a phoneme boundary rather than just differeces in the acoustics? |
| 94 | + |
| 95 | +Approach: |
| 96 | +Examine the **Auditory Mismatch Field** elicited in auditory cortex at ~180ms post stimulus onset by deviant stimuli in an **oddball paradigm**. |
| 97 | + |
| 98 | +Conclusion: Auditory cortex has access to phonemes, not just acoustic features, and they are recognized quickly. |
| 99 | + |
| 100 | +#### Semantics and syntax in the brain |
| 101 | +Finding evidence for high-level processes? (higher than phonemes) |
| 102 | + |
| 103 | +So called **violation studies** use EEG has investigated brain responses to when languages goes awry. |
| 104 | + |
| 105 | +N400: Semantic anomalies. (negativity 400 ms after the stimulus onset) |
| 106 | +P600: Syntactic anomalies. (positivity 600 ms after the stimulus onset) |
| 107 | + |
| 108 | +Progression from smaller unit to larger unit in terms of time. |
| 109 | + |
| 110 | +#### Putting two words together |
| 111 | +Combining two lexical items involves at least three processes |
| 112 | +- Syntactic composition |
| 113 | +- Logico-semantic composition (properties combine to to form set of entities) |
| 114 | +- Conceptual composition (features combine) |
| 115 | + |
| 116 | +What aspects of composition is the brain sentitive to? |
| 117 | + |
| 118 | +Bemis & Pylkäanen(2011) |
| 119 | + |
| 120 | +- two words vs. one word |
| 121 | + - Consonant string vs. psuedoword |
| 122 | +- Task (picture matching) |
| 123 | +- Composition vs. List |
| 124 | + - To account for the visual presence of two words |
| 125 | + - Task varied for composition and list stimuli to avoid composition |
| 126 | + |
| 127 | +Significant results, difference from two-word composition and one-word composition. |
| 128 | + |
| 129 | +Reflect conceptual composition! |
| 130 | + |
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