Inquiry: Post-Acquisition Recalibration

[ykmzn]

Hi,

I am using an LC-timsTOF (HT) for metabolomics, and I have a question about post-acquisition recalibration.

I perform post-acquisition recalibration using Internal calibration with time segments. After data acquisition, I recalibrate both m/z and ion mobility in the Bruker DataAnalysis application.

Will this post-acquisition recalibration be reflected in the .mzML file if I use TIMSCONVERT to convert the recalibrated .d files to .mzML?

Thank you in advance for your guidance.

Best regards,
Yuki