The WebUSB specification says:
The packetSize attribute declares the packet size employed by this endpoint and MUST be equal to the value of the wMaxPacketSize of the endpoint descriptor defining it. In a High-Speed, High-Bandwidth endpoint this value will include the multiplication factor provided by issuing multiple transactions per microframe. In a SuperSpeed device this value will include the multiplication factor provided by the bMaxBurst field of the SuperSpeed Endpoint Companion descriptor.
This field cannot simultaneously be equal to the value of the descriptor and also include the relevant multiplication factors.
The WebUSB specification says:
This field cannot simultaneously be equal to the value of the descriptor and also include the relevant multiplication factors.