Steps:
- decompose graph into components
- identify
pathway-gene-pathway and pathway-gene relationships
- define rules to extract pathway level modules
- annotations for pathway level known or rewired genetic interactions
Between Pathway Modules (BPM):
pathway-gene-pathway relationships for genes interacting within sub-network of linked pathways
Within Pathway Modules (WPM):
pathway-gene relationships for genes interacting within a single pathway
Steps:
pathway-gene-pathwayandpathway-generelationshipsBetween Pathway Modules (BPM):
pathway-gene-pathwayrelationships for genes interacting within sub-network of linked pathwaysWithin Pathway Modules (WPM):
pathway-generelationships for genes interacting within a single pathway