Implement a graph construction module that synthesizes nodes and edges into Directed Acyclic Graphs (DAGs). Key requirements:
- Enforce DAG properties (acyclicity, clear directionality).
- Handle branching and rejoining logic explicitly based on clinical significance.
- Validate structural correctness programmatically and through clinical annotation.
Implement a graph construction module that synthesizes nodes and edges into Directed Acyclic Graphs (DAGs). Key requirements: