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STR and VNTR annotation by motif composition for PacBio and Oxford Nanopore reads, and assemblies. The vamos suite contains two components, one to characterize the repeat motifs in a population using an `efficient` motif set, a subset of motifs that preserves motif sequence diversity while removing rare motifs, and annotation software that uses wraparound dynamic programming to annotate samples using tandem repeat and motif databases.
authors: Jingwen Ren and [Bida Gu]({% link Bida_Gu.md %})
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- image_path: /software/ctyperlogo.png
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title: "ctyper"
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excerpt: |
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Ctyper is a genotyping approach for pangenomes to detect alleles that are shared between a biobank (short-read sequencing) sample and a long-read pangenome for challenging and copy-number variable regions of the genome.
Software for mapping long reads (PacBio/Oxford Nanopore) or their assemblies to genomes. LRA implements an exact convex gap penalty for biologically meaningful gaps to discover structural variation.
A method to map short-read sequences into locus-specific pangenome graphs implemented as de Bruijn graphs to estimate tandem repeat variation by length and composition.
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