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STR and VNTR annotation by motif composition for PacBio and Oxford Nanopore reads, and assemblies. The vamos suite contains two components, one to characterize the repeat motifs in a population using an `efficient` motif set, a subset of motifs that preserves motif sequence diversity while removing rare motifs, and annotation software that uses wraparound dynamic programming to annotate samples using tandem repeat and motif databases.
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bioconda: vamos
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git: https://github.com/chaissonlab/vamos
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publication:
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publication: https://link.springer.com/article/10.1186/s13059-023-03010-y
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authors: Jingwen Ren and [Bida Gu]({% link Bida_Gu.md %})
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seg_ctyper:
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- image_path: /software/ctyperlogo.png
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title: "ctyper"
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excerpt: |
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Ctyper is a genotyping approach for pangenomes to detect alleles that are shared between a biobank (short-read sequencing) sample and a long-read pangenome for challenging and copy-number variable regions of the genome.
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bioconda: ctyper
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https://github.com/chaissonlab/ctyper
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git: https://github.com/chaissonlab/ctyper
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publication: https://www.nature.com/articles/s41588-025-02346-4
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author: [Walfred Ma]({% link Walfred_ma.md %})
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seg_lra:
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- image_path: /software/lra.png
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title: "LRA"
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excerpt: |
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Software for mapping long reads (PacBio/Oxford Nanopore) or their assemblies to genomes. LRA implements an exact convex gap penalty for biologically meaningful gaps to discover structural variation.
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git https://github.com/chaissonlab/lra
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git: https://github.com/chaissonlab/lra
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bioconda: lra
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publication: https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1009078
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author: Jingwen Ren
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seg_danbing-tk:
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- image_path: /software/danging-tk.png
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title: danbing-tk
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excerpt: |
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A method to map short-read sequences into locus-specific pangenome graphs implemented as de Bruijn graphs to estimate tandem repeat variation by length and composition.
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git: https://github.com/chaissonlab/danbing-tk
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publications: https://genome.cshlp.org/content/33/4/511.short, https://www.nature.com/articles/s41467-021-24378-0
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author: [Tony Tsung-Yu Lu]({% link tsungyu_lu.md %})
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---
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{% include feature_row id="seg_ctyper" type="left" %}
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{% include feature_row id="seg_vamos" type="left" %}
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{% include feature_row id="seg_lra" type="left" %}
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{% include feature_row id="seg_danbing-tk" type="left" %}

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